THCV for Parkinson’s Disease, as an Antipsychotic, to fight Obesity

Raw hemp analytes have remarkable medical benefits, but finding a source is not easy. Don’t worry, CBD Girl Next Door found one in North Carolina and is reviewing more, maybe one near you.

Boutique hemp farmers, which I define as farmers who both, grow an especially high quality medicinal strain of hemp and process their own with refined techniques, are out there and I found one. Down South Hemp in Erwin, NC has a fine strain and has a unique processing method which allows for a blend of beneficial analytes.

Most large processing agencies do not have such. It takes too much time and would raise the cost.

Down South Hemp’s recent COA on their Full Spectrum CBD Oil includes CBN, THC, CBDV, CBG, CBD, CBC, CBDA, CBGA, THCA, and THCV. This is an optimal blend of analytes in one product. The price reflects the boutique quality of a master craftsman.

50 mg Full Spectrum CBD Oil Capsules $130

When consumers shop for cheap CBD oils they will get cheap and everything that comes with it, honey. That is why CBD Watchdog is on duty to protect, inform and direct consumers to become wiser.

People like me, who eat raw for the THCA, CBGA and CBDA and use Full Spectrum CBD Oil, often have a difficult time finding a reputable raw source. Down South Hemp’s optimal blend solves the issue of finding a quality source of raw. I also eat raw for the nutritional benefits, but more about that in another article.

THCV has been researched in relation to medical benefits and the results indicate a positive effect, however, dosage and duration are unknown at this time. Always consult a physician.

It is important to note that smoking hemp is not recommended as the combustion reduces the amount of beneficial properties and smoking is not a natural body function. Also, smoking it has been shown to complicate diseases like Parkinson’s Disease. Oral application is recommended.

Regarding Parkinson’s Disease: “Given its antioxidant properties and its ability to activate CB2 but to block CB1 receptors, Δ9-THCV has a promising pharmacological profile for delaying disease progression in PD and also for ameliorating parkinsonian symptoms” Garcia, et. al. (2011).

In the world of mental issues: “Our findings suggest that THCV can enhance 5-HT1A receptor activation, and that some of its apparent antipsychotic effects may depend on this enhancement. We conclude that THCV has therapeutic potential for ameliorating some of the negative, cognitive and positive symptoms of schizophrenia” Cascio, et. al. (2015).

To fight obesity: “THCV is a new potential treatment against obesity-associated glucose intolerance with pharmacology different from that of CB1 inverse agonists/antagonists” Wargent, et. al. (2013).

Have a great day!

Love,

Your CBD Watchdog

  • García, C., Palomo-Garo, C., García-Arencibia, M., Ramos, J., Pertwee, R., & Fernández-Ruiz, J. (2011). Symptom-relieving and neuroprotective effects of the phytocannabinoid Δ⁹-THCV in animal models of parkinson’s disease. British Journal of Pharmacology, 163(7), 1495.

doi: 10.1111/j.1476-5381.2011.01278.x

  • Cascio, M. G., Zamberletti, E., Marini, P., Parolaro, D., & Pertwee, R. G. (2015). The phytocannabinoid, Δ9-tetrahydrocannabivarin, can act through 5-HT1Areceptors to produce antipsychotic effects: THCV, 5-HT1Aand schizophrenia. British Journal of Pharmacology, 172(5), 1305-1318. doi:10.1111/bph.13000
  • Wargent, E. T., Zaibi, M. S., Silvestri, C., Hislop, D. C., Stocker, C. J., Stott, C. G., . . . Cawthorne, M. A. (2013). The cannabinoid Δ(9)-tetrahydrocannabivarin (THCV) ameliorates insulin sensitivity in two mouse models of obesity. Nutrition & Diabetes, 3, e68.

Parkinsons Dis. 2016; 2016: 1279042.Published online 2016 Dec 5. doi: 10.1155/2016/1279042PMCID: PMC5165161PMID: 28050308

Marijuana Compounds: A Nonconventional Approach to Parkinson’s Disease Therapy

Mariana Babayeva, * Haregewein AssefaParamita BasuSanjeda Chumki, and Zvi Loewy

It is not wise to use a product without full transparency. Insist on a verifiable full profile COA with any hemp product. Identify the testing lab with a header on the lab work. Do not accept a lab report without identifying language and contact information. Identify that COA with a correlating batch number.

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